Known as "AB," Takyi is a musician, actress, and theatre director. She's played a number of roles in Ghanaian television series such as Home Sweet Home, Hotel St. James, Sun City, and Bloody Mary, as well as leading and supporting roles in stage productions such as The Diary of Adam and Eve, Langbodo, Anowa, and an adapted version of The Vagina Monologues. Abena holds a Bachelor of Fine Arts Degree from the School of Performing Arts, University of Ghana.